# Medical Toxicology * **Definition:** The study and specialty focused on the diagnosis, prevention, evaluation, treatment, and monitoring of injury and illness resulting from exposures to drugs and chemicals, including the effects of these substances on human health. * **Taxonomy:** Specialties / Medical Toxicology ## News * Selected news on the topic of **Medical Toxicology**, for healthcare technology leaders * 844 news items are in the system for this topic * Posts have been filtered for tech-related keywords | Date | Title | Source | | --- | --- | --- | | 5/13/2025 | [**Organoids Market Surges with Applications in Disease Modeling and Personalized Medicine - Download Insights Today! Valuates Reports**](https://www.prnewswire.com/news-releases/organoids-market-surges-with-applications-in-disease-modeling-and-personalized-medicine--download-insights-today-valuates-reports-302454113.html) | [[PR Newswire]] | | 5/13/2025 | [**Organoids Market Surges with Applications in Disease Modeling and Personalized Medicine**](https://finance.yahoo.com/news/organoids-market-surges-applications-disease-153400939.html) | [[Yahoo Finance]] | | 1/31/2025 | [**High Throughput Screening (HTS) Market to Grow by USD 19.9 Billion (2024-2028), Boosted by Rising R&D Investments, with AI Redefining Market Landscape - Technavio**](https://www.prnewswire.com/news-releases/high-throughput-screening-hts-market-to-grow-by-usd-19-9-billion-2024-2028-boosted-by-rising-rd-investments-with-ai-redefining-market-landscape---technavio-302364447.html) | [[PR Newswire]] | | 12/27/2024 | [**Pioneering Toxicology Research Takes Center Stage at 2025 ACMT Annual Meeting in Vancouver**](https://www.globenewswire.com/news-release/2024/12/27/3002364/0/en/Pioneering-Toxicology-Research-Takes-Center-Stage-at-2025-ACMT-Annual-Meeting-in-Vancouver.html) | [[Globe Newswire]] | | 12/27/2024 | [**Pioneering Toxicology Research Takes Center Stage at 2025 ACMT Annual Meeting in Vancouver**](https://www.morningstar.com/news/globe-newswire/9324561/pioneering-toxicology-research-takes-center-stage-at-2025-acmt-annual-meeting-in-vancouver) | [[Morningstar]] | | 12/27/2024 | [**Pioneering Toxicology Research Takes Center Stage at 2025 ACMT Annual Meeting in Vancouver**](https://markets.businessinsider.com/news/stocks/pioneering-toxicology-research-takes-center-stage-at-2025-acmt-annual-meeting-in-vancouver-1034177218) | [[Business Insider Markets]] | | 12/17/2024 | [**Caris Life Sciences Appoints Dr. James Hamrick as Chairman of the Caris Precision ...**](https://www.prnewswire.com/news-releases/caris-life-sciences-appoints-dr-james-hamrick-as-chairman-of-the-caris-precision-oncology-alliance-302332807.html) | [[PR Newswire]] | | 12/5/2024 | [**SafeBridge Consultants Hosts Global Potent Compound Congress and Expo©**](https://www.prnewswire.com/news-releases/safebridge-consultants-hosts-global-potent-compound-congress-and-expo-302322033.html) | [[PR Newswire]] | | 11/22/2024 | [**Biosimulation Market to Hit USD 9.18 Billion by 2029 with 16.7AGR - MarketsandMarkets™.**](https://www.globenewswire.com/news-release/2024/11/22/2985889/0/en/Biosimulation-Market-to-Hit-USD-9-18-Billion-by-2029-with-16-7-CAGR-MarketsandMarkets.html) | [[Globe Newswire]] | | 11/19/2024 | [**Simulations Plus to Participate in the BTIG Digital Health Forum**](http://www.businesswire.com/news/home/20241119690966/en/Simulations-Plus-to-Participate-in-the-BTIG-Digital-Health-Forum/?feedref=JjAwJuNHiystnCoBq_hl-RLXHJgazfQJNuOVHefdHP-D8R-QU5o2AvY8bhI9uvWSD8DYIYv4TIC1g1u0AKcacnnViVjtb72bOP4-4nHK5ieT3WxPE8m_kWI77F87CseT) | [[Business Wire]] | | 11/7/2024 | [**The Inner Circle acknowledges, Alan H. Hall, MD as a Pinnacle Lifetime Member**](https://www.prnewswire.com/news-releases/the-inner-circle-acknowledges-alan-h-hall-md-as-a-pinnacle-lifetime-member-302299093.html) | [[PR Newswire]] | | 11/7/2024 | [**The Inner Circle acknowledges, Alan H. Hall, MD as a Pinnacle Lifetime Member**](https://finance.yahoo.com/news/inner-circle-acknowledges-alan-h-194600008.html) | [[Yahoo Finance]] | | 11/4/2024 | [**Statement on Fentanyl “Exposure” Laws Issued by the American College of Medical Toxicology**](https://www.globenewswire.com/news-release/2024/11/04/2974298/0/en/Statement-on-Fentanyl-Exposure-Laws-Issued-by-the-American-College-of-Medical-Toxicology.html) | [[Globe Newswire]] | | 11/4/2024 | [**Statement on Fentanyl “Exposure” Laws Issued by the American College of Medical Toxicology**](https://finance.yahoo.com/news/statement-fentanyl-exposure-laws-issued-165700813.html) | [[Yahoo Finance]] | | 10/14/2024 | [**No Evidence that Tampons Cause Metal Poisoning: American College of Medical Toxicology Issues Position Statement**](https://www.globenewswire.com/news-release/2024/10/14/2962820/0/en/No-Evidence-that-Tampons-Cause-Metal-Poisoning-American-College-of-Medical-Toxicology-Issues-Position-Statement.html) | [[Globe Newswire]] | | 10/3/2024 | [**Global Preclinical CRO Market Size to Hit USD 21.48 billion by 2033 - Straits Research**](https://www.globenewswire.com/news-release/2024/10/03/2957862/0/en/Global-Preclinical-CRO-Market-Size-to-Hit-USD-21-48-billion-by-2033-Straits-Research.html) | [[Globe Newswire]] | | 9/30/2024 | [**Mifepristone and Misoprostol are Not “Controlled Dangerous Substances”: The American College of Medical Toxicology Issues Position Statement**](https://www.globenewswire.com/news-release/2024/09/30/2955392/0/en/Mifepristone-and-Misoprostol-are-Not-Controlled-Dangerous-Substances-The-American-College-of-Medical-Toxicology-Issues-Position-Statement.html) | [[Globe Newswire]] | | 9/27/2024 | [**CDC Announces National Partners Cooperative Agreement Recipients: American College of Medical Toxicology Among Awardees**](https://www.globenewswire.com/news-release/2024/09/27/2954611/0/en/CDC-Announces-National-Partners-Cooperative-Agreement-Recipients-American-College-of-Medical-Toxicology-Among-Awardees.html) | [[Globe Newswire]] | | 9/27/2024 | [**CDC Announces National Partners Cooperative Agreement Recipients: American College of Medical Toxicology Among Awardees**](https://markets.businessinsider.com/news/stocks/cdc-announces-national-partners-cooperative-agreement-recipients-american-college-of-medical-toxicology-among-awardees-1033804504) | [[Business Insider Markets]] | | 9/26/2024 | [**CDC Announces National Partners Cooperative Agreement Recipients: American College of Medical Toxicology Among Awardees**](https://www.morningstar.com/news/globe-newswire/9237769/cdc-announces-national-partners-cooperative-agreement-recipients-american-college-of-medical-toxicology-among-awardees) | [[Morningstar]] | | 9/10/2024 | [**Preclinical CRO Market Expands at 6.5AGR, Driven by Advances in Drug Discovery and ...**](https://www.prnewswire.com/news-releases/preclinical-cro-market-expands-at-6-5-cagr-driven-by-advances-in-drug-discovery-and-outsourcing-trends-market-research-intellect-302243524.html) | [[PR Newswire]] | | 8/28/2024 | [**Simulations Plus to Participate in the Morgan Stanley 22nd Annual Global Healthcare Conference**](http://www.businesswire.com/news/home/20240828878863/en/Simulations-Plus-to-Participate-in-the-Morgan-Stanley-22nd-Annual-Global-Healthcare-Conference/?feedref=JjAwJuNHiystnCoBq_hl-RLXHJgazfQJNuOVHefdHP-D8R-QU5o2AvY8bhI9uvWSD8DYIYv4TIC1g1u0AKcacnnViVjtb72bOP4-4nHK5ieT3WxPE8m_kWI77F87CseT) | [[Business Wire]] | | 8/28/2024 | [**Simulations Plus to Participate in the Morgan Stanley 22nd Annual Global Healthcare Conference**](http://www.businesswire.com/news/home/20240828878863/en/Simulations-Plus-to-Participate-in-the-Morgan-Stanley-22nd-Annual-Global-Healthcare-Conference/?feedref=JjAwJuNHiystnCoBq_hl-Q-tiwWZwkcswR1UZtV7eGe24xL9TZOyQUMS3J72mJlQ7fxFuNFTHSunhvli30RlBNXya2izy9YOgHlBiZQk2LOzmn6JePCpHPCiYGaEx4DL1Rq8pNwkf3AarimpDzQGuQ==) | [[Business Wire]] | | 8/5/2024 | [**Renowned surgical oncologist takes leadership role at NYU Grossman Long Island School of Medicine**](https://www.news-medical.net/news/20240805/Renowned-surgical-oncologist-takes-leadership-role-at-NYU-Grossman-Long-Island-School-of-Medicine.aspx) | [[News Medical Net]] | | 8/24/2023 | [**Journal of Medical Toxicology**](https://medicalxpress.com/journals/journal-of-medical-toxicology/) | [[MedicalXpress]] | ## Specialty Overview (Some LLM-derived content — please confirm with above primary sources) ### Key Players - **American College of Medical Toxicology (ACMT)**: A nonprofit association of physicians specializing in medical toxicology, focusing on the prevention and treatment of injuries and illnesses from drug and chemical exposures. - **Dr. Michael Lynch**: An emergency physician and medical toxicologist at the University of Pittsburgh Medical Center, known for his work in toxicology telemedicine. - **Medicilon**: A preclinical drug development service provider that emphasizes toxicology and safety evaluation in drug discovery. - **Dr. Cyrus Rangan**: A medical toxicologist who evaluates the realism of poison scenes in media and contributes to public understanding of toxicology. - **National Toxicology Program**: A U.S. government agency that conducts research and provides information on the health effects of environmental substances, including fluoride. - **Washington Poison Center**: A nonprofit organization providing 24/7 medical advice on poison and drug exposure, enhancing community health and safety. - **Centers for Disease Control and Prevention (CDC)**: A national public health institute in the United States that provides funding and support for public health initiatives, including those related to medical toxicology. - **Schrödinger, Inc.**: A company that develops computational platforms to predict toxicology risks early in drug discovery. - **Wildcat DX, LLC**: A healthcare company that has acquired Navis Clinical Laboratories, enhancing its toxicology testing services. - **Proscia**: A digital pathology company that collaborates with Instem to enhance toxicology research through integrated software solutions. - **Neurizon Therapeutics Limited**: A biotechnology company developing treatments for neurodegenerative diseases, including ALS, with a focus on toxicology studies for drug safety. - **Stanford Medicine**: Researchers developing gene-screening methods to mitigate chemotherapy-induced heart damage. - **BioIVT**: A provider of biospecimen solutions and research services, focusing on enhancing ADME-Tox products and services. - **TRC Companies, Inc.**: A provider of environmental solutions that has acquired Paustenbach & Associates to enhance capabilities in health hazard assessments. - **Clarivate Plc**: A global leader in providing data and analytics to accelerate drug development, including the launch of the OFF-X™ platform for safety insights. - **Purdue Pharma**: A pharmaceutical company involved in the development of nalmefene hydrochloride, an opioid antagonist used for reversing opioid effects. ### Partnerships and Collaborations - **ACMT and CDC**: ACMT has received a five-year cooperative agreement from the CDC to enhance public health systems and services, focusing on the role of medical toxicologists in public health. - **Medicilon and Jiangsu Hengrui Pharmaceuticals**: A strategic collaboration focusing on preclinical evaluation of new drug modalities, including toxicology studies. - **EpicentRx and Queensland University of Technology**: Collaboration to develop RRx-001 as a neuroprotective agent against neurotoxic chemical exposures. - **UPMC and eVisit**: eVisit has acquired tele-consult technology from UPMC to enhance telehealth capabilities, improving access to medical toxicology consultations. - **Schrödinger and NVIDIA**: Collaboration to leverage AI technologies for predicting toxicity risks in drug development. - **Revive Therapeutics Ltd. and Defence R&D Canada**: Collaboration to evaluate Bucillamine as a treatment for nerve agent exposure. - **Instem and Proscia**: A partnership aimed at integrating data from Provantis into Concentriq's digital pathology workflows to enhance toxicology assessments. - **Clarivate and Cortellis**: The OFF-X™ platform integrates with Cortellis Drug Discovery Intelligence™ to streamline safety information access. - **Catawba Research and PharmaLegacy Laboratories**: A strategic partnership aimed at enhancing preclinical and clinical research capabilities, focusing on drug development and access to the Chinese market. - **ACMT and other public health organizations**: ACMT collaborates with 47 other public health organizations, including the American Medical Association and the American Academy of Pediatrics, under the CDC's National Partners program. - **BioIVT and ZenBio**: Acquisition to enhance BioIVT's ADME product portfolio and meet researchers' needs. - **Scientist.com and Evotec SE**: A partnership that allows registered users to access Evotec's drug discovery services through an online platform, enhancing research efficiency. - **Simulations Plus and various pharmaceutical companies**: Partnerships to enhance drug discovery processes using advanced biosimulation technologies. - **City of Hope and SWOG Cancer Research Network**: Collaborating to design a Phase II/III trial investigating the use of CBM588 in advanced cancer patients. - **Caris Precision Oncology Alliance**: A global network of 96 cancer centers and institutions collaborating to improve clinical outcomes for cancer patients. ### Innovations, Trends, and Initiatives - **Toxicology Telemedicine**: The UPMC Toxicology Telemedicine Bridge Clinic aims to provide remote consultations for toxicology cases, improving access to specialized care. - **ACMT Annual Scientific Meeting**: An event showcasing advancements in medical toxicology research, including topics on substance use disorder management and toxicology education. - **Public Health Capacity Building**: ACMT's project aims to strengthen the capacity of medical toxicologists through risk communication support, enhanced training, and mentorship networks. - **Alternative Toxicological Methods (NAMs)**: New methodologies aimed at replacing animal testing in chemical safety assessments, supported by federal agencies. - **Computational Toxicology Initiative**: Schrödinger's initiative funded by the Gates Foundation aims to improve drug safety profiles and reduce development failures. - **SafeBridge Global Potent Compound Congress**: An upcoming event focusing on innovations in drug discovery and safety related to potent compounds, emphasizing the importance of toxicology. - **Research on Poison Centers**: Studies indicate a significant rise in severe cases reported to poison centers, highlighting the need for improved public health strategies and education. - **Gene-Screening Method for Chemotherapy Toxicity**: Stanford researchers identified the CA12 gene's role in doxorubicin-induced heart damage and discovered a protective drug, indisulam. - **OFF-X™ Platform**: Clarivate's platform enhances safety insights for biopharma companies, integrating preclinical toxicity data and clinical adverse event data. - **Nalmefene Study**: Purdue Pharma is conducting a study on nalmefene hydrochloride injection in emergency department settings to evaluate its effectiveness compared to naloxone in reversing acute opioid toxicity. - **Research on Delta-8 THC Exposures**: Recent studies highlight trends in calls to poison centers regarding delta-8 THC exposures, indicating significant public health implications related to cannabis products. - **Human Exposome Project**: A proposed large-scale initiative to understand the cumulative environmental exposures affecting health, similar to the Human Genome Project. - **Delta-8 THC Education**: Increased focus on educating the public about the risks associated with delta-8 THC, particularly regarding child safety and accidental exposures. - **ADMET Predictor 12.0**: An upgraded platform by Simulations Plus that integrates machine learning for improved predictive accuracy in drug discovery. - **AI in Clinical Trials**: The market for AI in clinical trials is projected to grow significantly, driven by the need for improved drug approval processes and management of toxicity. - **Fluoride Research**: Recent studies have indicated potential neurological risks associated with high fluoride exposure, particularly in children, prompting discussions on water fluoridation levels. - **Chip-R1™ Launch**: Emulate's new organ-on-chip technology minimizes drug absorption and enhances biological modeling for drug response predictions. - **AI in Drug Discovery**: Artificial intelligence is being utilized to enhance drug research and development, particularly in predicting drug performance and toxicity. - **Organ-on-Chip Market Growth**: The global organ-on-chip market is projected to grow significantly, driven by advancements in tissue engineering and personalized medicine. - **Generative AI in Drug Discovery**: Medgnosis's AI system can generate over 400 novel compounds in five seconds, significantly reducing the time and cost of traditional drug discovery. ### Challenges and Concerns - **Environmental Health Issues**: Concerns regarding exposure to heavy metals and their links to cardiovascular diseases, emphasizing the importance of toxicology in public health. - **Toxicology Risks in Drug Development**: The need for early identification of toxicology risks to prevent costly development failures. - **Toxicity of New Compounds**: The need for comprehensive toxicological data for new drugs and chemicals to ensure safety and efficacy. - **Toxicity in Drug Development**: Ensuring the safety and minimizing toxicity of drugs is critical, particularly in the context of new drug modalities and therapies targeting the blood-brain barrier. - **Severe Cases in Poison Centers**: A 234% increase in intentional exposures leading to death over 15 years indicates a growing public health crisis related to toxic exposures. - **Regulatory Compliance**: The need for compliance with Good Laboratory Practice (GLP) standards in toxicology studies poses challenges for drug developers. - **Rising Delta-8 THC Exposures**: A nearly 80% increase in delta-8 THC exposures reported to poison centers, particularly among children, raises concerns about safety and regulation. - **Toxicity of CAR-T Therapy**: Concerns about the toxicity and fertility risks associated with CAR-T therapy are prompting researchers to explore alternative approaches. - **Public Awareness of Drug Risks**: There is a lack of awareness among substance users regarding the health risks associated with their drug use, as highlighted by misconceptions about the dangers of methamphetamine compared to fentanyl. - **Environmental and Genetic Factors in Precision Medicine**: The challenge of integrating environmental exposures with genetic data to improve health outcomes. - **Plastic Pollution and Health**: The health impacts of microplastics and the need for further research on their effects on human health. - **Fentanyl Legislation in Florida**: ACMT has expressed concerns about Florida's SB 718 legislation, which categorizes reckless exposure of first responders to fentanyl as a second-degree felony, arguing it perpetuates misinformation and could hinder emergency responders' effectiveness. - **Access to Naloxone**: Research indicates that individuals in low-income areas have limited access to naloxone, a critical opioid reversal drug, raising concerns about opioid overdose risks. - **Regulatory Gaps in Tobacco Products**: Concerns regarding the FDA's limited authority over nicotine analogues and the potential health risks associated with new e-cigarette products. - **Public Health Debate**: Ongoing debates about the safety and efficacy of fluoride in drinking water, with some advocating for its removal based on health concerns, while public health organizations support its use for dental health. - **Mifepristone and Misoprostol Classification**: Concerns over new laws classifying these medications as controlled substances, potentially impacting patient care and access. - **Fluoride Exposure Risks**: Concerns regarding the potential link between high fluoride levels in drinking water and lower IQ in children, as highlighted by recent government reports. - **Privacy Concerns in Digital Health Monitoring**: The use of digital health monitoring technologies raises significant privacy and data protection issues. - **Reimbursement Challenges for Patient Navigation Services**: Despite new billing codes for patient navigation services, oncology practices face difficulties in securing reimbursement.