# Gut Microbiome * **Definition:** The complex ecosystem of trillions of bacteria, fungi, viruses, and other microorganisms residing in the digestive system, which plays a crucial role in digestion, metabolism, immune function, and overall health. * **Taxonomy:** Healthcare Topics / Gut Microbiome ## News * Selected news on the topic of **Gut Microbiome**, for healthcare technology leaders * 4.4K news items are in the system for this topic * Posts have been filtered for tech and healthcare-related keywords | Date | Title | Source | | --- | --- | --- | | 4/24/2025 | [**How the gut microbiome affects mental health**](https://www.news-medical.net/whitepaper/20250424/How-the-gut-microbiome-affects-mental-health.aspx) | [[News Medical Net]] | | 4/22/2025 | [**Walnut consumption curbs inflammation and may reduce colon cancer risk, clinical trial finds**](https://medicalxpress.com/news/2025-04-walnut-consumption-curbs-inflammation-colon.html) | [[MedicalXpress]] | | 4/19/2025 | [**Why everyone got obsessed with gut health - Yahoo**](https://www.yahoo.com/lifestyle/why-everyone-got-obsessed-gut-065801316.html) | [[Yahoo]] | | 4/7/2025 | [**The gut microbiome as a predictive factor for kidney rejection**](https://medicalxpress.com/news/2025-04-gut-microbiome-factor-kidney.html) | [[MedicalXpress]] | | 3/26/2025 | [**Gut microbiome serves as a 'second brain' to regulate our bodies, says researcher**](https://medicalxpress.com/news/2025-03-gut-microbiome-brain-bodies.html) | [[MedicalXpress]] | | 2/24/2025 | [**Study shows tagatose may combat antibiotic-resistant C. difficile infections**](https://medicalxpress.com/news/2025-02-tagatose-combat-antibiotic-resistant-difficile.html) | [[MedicalXpress]] | | 11/18/2024 | [**Are you what you eat? How much does diet shape your gut microbiome? - The Seattle Times**](https://www.seattletimes.com/life/wellness/are-you-what-you-eat-how-much-does-diet-shape-your-gut-microbiome/) | [[Seattle Times]] | | 11/17/2024 | [**Gut microbiome found to play key role in chronic disease progression**](https://www.news-medical.net/news/20241115/Gut-microbiome-found-to-play-key-role-in-chronic-disease-progression.aspx) | [[News Medical Net]] | | 11/11/2024 | [**Gut microbiome dynamics linked to rheumatoid arthritis progression**](https://medicalxpress.com/news/2024-11-gut-microbiome-dynamics-linked-rheumatoid.html) | [[MedicalXpress]] | | 10/9/2024 | [**Virtual Healthcare October 2024**](https://www.healthitanswers.net/virtual-healthcare-october-2024/) | [[Health IT Answers]] | | 10/3/2024 | [**Digbi Health to Present Groundbreaking Study on Gut Microbiome's Role in Enhancing ...**](https://finance.yahoo.com/news/digbi-health-present-groundbreaking-study-150000513.html) | [[Yahoo Finance]] | | 10/3/2024 | [**Digbi Health to Present Groundbreaking Study on Gut Microbiome's Role in Enhancing Endogenous GLP-1 Production at 2024 Obesity Society Conference**](http://www.businesswire.com/news/home/20241003457990/en/Digbi-Health-to-Present-Groundbreaking-Study-on-Gut-Microbiomes-Role-in-Enhancing-Endogenous-GLP-1-Production-at-2024-Obesity-Society-Conference/?feedref=JjAwJuNHiystnCoBq_hl-RLXHJgazfQJNuOVHefdHP-D8R-QU5o2AvY8bhI9uvWSD8DYIYv4TIC1g1u0AKcacnnViVjtb72bOP4-4nHK5ieT3WxPE8m_kWI77F87CseT) | [[Business Wire]] | | 10/3/2024 | [**Digbi Health to Present Groundbreaking Study on Gut Microbiome's Role in Enhancing Endogenous GLP-1 Production at 2024 Obesity Society Conference**](https://www.businesswire.com/news/home/20241003457990/en/Digbi-Health-to-Present-Groundbreaking-Study-on-Gut-Microbiomes-Role-in-Enhancing-Endogenous-GLP-1-Production-at-2024-Obesity-Society-Conference/) | [[Business Wire]] | | 10/2/2024 | [**Gut Microbiome Health Tech Innovator, Ixcela Launches Virtual Clinic to Ease Cancer ...**](https://www.prnewswire.com/news-releases/gut-microbiome-health-tech-innovator-ixcela-launches-virtual-clinic-to-ease-cancer-symptoms-after-landmark-roper-st-francis-healthcare-pilot-302264955.html) | [[PR Newswire]] | | 10/1/2024 | [**Gut Microbiome Health Tech Innovator, Ixcela Launches Virtual Clinic to Ease Cancer Symptoms After Landmark Roper St. Francis Healthcare Pilot**](https://www.morningstar.com/news/pr-newswire/20241002ne21058/gut-microbiome-health-tech-innovator-ixcela-launches-virtual-clinic-to-ease-cancer-symptoms-after-landmark-roper-st-francis-healthcare-pilot) | [[Morningstar]] | | 9/18/2024 | [**Revolutionizing early life nutrition: Lallemand Health Solutions' latest probiotic innovations**](https://www.nutritioninsight.com/news/revolutionizing-early-life-nutrition-lallemand-health-solutions-latest-probiotic-innovations.html) | nutritioninsight.com | | 9/14/2024 | [**Emerging Frontiers: The Gut Microbiome's Role in Enhancing Cancer Immunotherapy and Treatment Outcomes**](https://www.pharmacytimes.com/view/emerging-frontiers-the-gut-microbiome-s-role-in-enhancing-cancer-immunotherapy-and-treatment-outcomes) | [[Pharmacy Times]] | | 9/12/2024 | [**Scientists invent tool to see how 'healthy' your gut microbiome is - does it work?**](https://www.yahoo.com/news/scientists-invent-tool-see-healthy-153801317.html) | [[Yahoo]] | | 9/11/2024 | [**32 Biosciences Emerges from Stealth Mode with New Approach to Gut Microbiome Medicine**](https://www.prnewswire.com/news-releases/32-biosciences-emerges-from-stealth-mode-with-new-approach-to-gut-microbiome-medicine-302244612.html) | [[PR Newswire]] | | 9/9/2024 | [**Scientists unlock predictive healthcare with innovative gut microbiome analytical tool**](https://www.nutritioninsight.com/news/scientists-unlock-predictive-healthcare-with-innovative-gut-microbiome-analytical-tool.html) | nutritioninsight.com | | 9/3/2024 | [**Computational tool can measure the health of a person's gut microbiome**](https://medicalxpress.com/news/2024-09-tool-health-person-gut-microbiome.html) | [[MedicalXpress]] | | 9/2/2024 | [**New computational tool accurately assesses health through gut microbiome analysis**](https://www.news-medical.net/news/20240903/New-computational-tool-accurately-assesses-health-through-gut-microbiome-analysis.aspx) | [[News Medical Net]] | | 6/26/2024 | [**Study offers insights into gut microbiome diversity and type 2 diabetes risk**](https://www.news-medical.net/news/20240626/Study-offers-insights-into-gut-microbiome-diversity-and-type-2-diabetes-risk.aspx) | [[News Medical Net]] | | 6/26/2024 | [**Chemotherapy could disrupt gut microbiome in patients with breast cancer**](https://medicalxpress.com/news/2024-06-chemotherapy-disrupt-gut-microbiome-patients.html) | [[MedicalXpress]] | | 6/25/2024 | [**Study links gut microbiome changes to increased risk of type 2 diabetes**](https://medicalxpress.com/news/2024-06-links-gut-microbiome-diabetes.html) | [[MedicalXpress]] | ## Topic Overview (Some LLM-derived content — please confirm with above primary sources) ### Key Players - **King's College London**: Leading the Human Gut Microbiome Atlas project to enhance understanding of gut microorganisms and their influence on diseases. - **APC Microbiome Ireland**: Conducted studies on the impact of Western diets on gut microbiome and chronic diseases. - **BiomeSense**: Developed GutLab technology for at-home gut microbiome monitoring, collaborating with Pendulum Therapeutics to study Akkermansia muciniphila. - **Mayo Clinic**: A leading healthcare institution that developed the Gut Microbiome Wellness Index 2, a computational tool for analyzing gut health. - **32 Biosciences**: A company focused on microbiome diagnostic management tools and interventions, developing GB-0001 to standardize gut microbiome health measurement. - **MICROBIOMES4SOY**: An EU-funded Horizon project aimed at promoting healthier plant-based diets through understanding microbiomes. - **Rutgers University**: Developed a method to identify essential gut microbes crucial for human health, enhancing precision nutrition and personalized therapies. - **Cornell University**: Conducted a study on the varying health effects of dietary fiber based on individual gut microbiome composition. - **Weill Cornell Medicine**: Collaborating with Baylor University to explore fecal microbiota transplantation tailored to individual gut microbiomes. - **Cleveland Clinic**: Research led by Dr. Stanley Hazen exploring the role of gut microbiome in chronic diseases and developing microbial-targeting therapies. - **MaaT Pharma**: Developing microbiome-driven therapies for cancer patients, focusing on gastrointestinal acute Graft-versus-Host Disease. - **Jona**: A microbiome profiling startup that utilizes AI to help users understand their gut health and has revamped its user interface based on feedback. - **InnoGI Technologies**: A company specializing in dynamic gut modeling and gastrointestinal research. - **Acurx Pharmaceuticals**: Conducted a head-to-head comparison of gut microbiome changes associated with their antibiotic ibezapolstat versus others, showing less impact on microbiome diversity. - **Brigham and Women's Hospital**: Collaborated with the Broad Institute and Harvard T.H. Chan School of Public Health on a comprehensive study linking gut microbiome to type 2 diabetes. - **European Microbiome Innovation for Health (EMIH)**: An association focused on advancing microbiome drug development and harmonizing regulatory frameworks. - **Dr. Connor Prosty**: A researcher at McGill University who has conducted studies linking the gut microbiome to chronic disease progression. - **City of Hope**: A cancer research and treatment center conducting studies on gut microbiome's impact on cancer therapies. - **University of California, Irvine**: Conducted significant research linking circadian rhythm disruptions to colorectal cancer progression via gut microbiome alterations. ### Partnerships and Collaborations - **NIST and Collaborators**: Collaborating to analyze human fecal mixtures for developing new medical treatments derived from the gut microbiome. - **EMIH and MTIG**: A collaboration aimed at advancing microbiome drug development and ensuring equitable access to microbiome therapies. - **King's College London and International Researchers**: Collaborating on the Human Gut Microbiome Atlas to study gut bacteria across various diseases. - **BiomeSense and Pendulum Therapeutics**: Collaborating on a study to evaluate at-home gut microbiome monitoring technology focusing on Akkermansia muciniphila. - **University of Vienna**: Collaborated with an international team to study the effects of Parkinson's disease drugs on the gut microbiome. - **AWI-Gen Partnership**: A collaboration focused on genomic studies in African populations to understand health factors affecting gut microbiome composition. - **Baylor University and Weill Cornell Medicine**: Collaboration to develop personalized treatments for gut microbiome diseases. - **ZOE**: Co-founded by Professor Dr. Tim Spector, focusing on the relationship between diet and gut microbiome composition. - **Leeds Researchers**: Collaborated on a study linking gut microbiome changes to the onset of rheumatoid arthritis. - **Clardy Lab and Ramnik Xavier's Lab**: Collaboration advancing understanding of gut bacteria interactions with the immune system. - **MRM Health and industry veterans**: Strengthening executive team to enhance clinical development of microbiome therapies. - **Brigham and Women's Hospital, Broad Institute, Harvard T.H. Chan School of Public Health**: Collaborated on a study analyzing gut microbiome data related to type 2 diabetes. - **InnoGI Technologies and Bac3Gel**: Formed a partnership for exclusive distribution rights of Gut3Beads for colonic research. - **Kihealth and Genova Diagnostics**: Partnered to enhance access to gut health testing through retail pharmacies. - **Bonumose, Inc.**: Collaborating with UConn to explore the commercial potential of tagatose as a prebiotic for gut health. - **Ohio State University and Nationwide Children's Hospital**: Collaborated on research exploring the gut microbiome's role in cancer treatment effectiveness. - **University College Cork**: Conducted research on the gut microbiome's impact on wild birds, contributing to conservation biology. - **Ixcela and Roper St. Francis Healthcare**: Collaborated to launch the Ixcela Cancer Support Program aimed at enhancing cancer patient care through gut microbiome health. ### Innovations, Trends, and Initiatives - **Human Gut Microbiome Atlas**: A comprehensive dataset aimed at understanding how gut microorganisms influence diseases, facilitating personalized treatment approaches. - **Gut Microbiome Wellness Index 2**: Developed by Mayo Clinic, this tool analyzes gut microbiome health with over 80% accuracy. - **Gut Microbiome Testing**: Redcliffe Labs launched a non-invasive gut microbiome test to provide insights into health and personalized dietary recommendations. - **Research on Gut-Brain Axis**: Exploring the bi-directional communication between gut microbiome and neurological health, with implications for mental health treatments. - **GutLab by BiomeSense**: An at-home monitoring technology that allows users to track their gut microbiome, potentially paving the way for precision medicine. - **Personalized Treatments**: Research emphasizes the need for individualized treatment strategies for gut microbiome diseases due to unique microbiome compositions. - **GB-0001 by 32 Biosciences**: A diagnostic tool aimed at standardizing gut microbiome health measurement to enhance clinical decision-making. - **Dietary Impact Studies**: Research showing how different dietary proteins affect gut microbiome composition and health outcomes. - **Gut3Beads**: Innovative hydrogel beads developed for in vitro colonic research to enhance microbiome studies. - **Precision Nutrition**: The study from Cornell University emphasizes the need for personalized dietary recommendations based on gut microbiome diversity. - **Machine Learning in Microbiome Studies**: Utilizing machine learning to predict dietary impacts on gut microbiome composition with high accuracy. - **Ixcela Cancer Support Program**: Focuses on personalized gut microbiome interventions to reduce cancer treatment side effects, showing promising results in pilot studies. - **Fecal Microbiota Transplantation (FMT)**: An emerging therapeutic option showing efficacy in treating Clostridioides difficile infection and potential in cancer immunotherapy. - **TOPOSCORE Development**: A new method for predicting treatment response in cancer patients based on gut microbiome composition. - **Microbiome Augmentation Therapies**: DFI is developing therapies focusing on the microbiome's role in health, with ongoing clinical trials. - **Fecal Microbiome Research**: Recent FDA approvals of drugs derived from processed human stool samples highlight the potential of fecal microbes in treating infections. - **AI in Microbiome Profiling**: Jona's platform uses AI to provide insights into gut health, addressing various disorders linked to microbiome imbalances. - **Microbiome Sequencing Services**: The market is projected to grow significantly, driven by personalized medicine and advancements in sequencing technologies. ### Challenges and Concerns - **Rheumatoid Arthritis**: Changes in gut microbiome associated with the onset of rheumatoid arthritis, highlighting the need for further research. - **Microbiome Diversity**: Modern lifestyles are diminishing gut microbiome diversity, which is crucial for maintaining gut health. - **Antibiotic Resistance**: Research highlights the health risks posed by certain gut bacteria, emphasizing the need for understanding microbial interactions. - **Efficacy of Microbiome Therapies**: Microbiome-based therapies, such as fecal microbiota transplants, face challenges in consistent efficacy due to survival issues of new microbes in patients. - **Defining 'Healthy' Microbiome**: Experts have raised concerns about the practical utility of tools like the Gut Microbiome Wellness Index 2, questioning the definition of a healthy gut microbiome. - **Linking Microbiome to Chronic Diseases**: Despite promising findings, establishing clear connections between microbiome composition and chronic diseases remains complex and requires further research. - **Dysbiosis**: Imbalances in gut microbiome linked to various health conditions, including inflammatory diseases and chronic conditions. - **Dysbiosis in Transplant Patients**: Unhealthy gut microbiome patterns linked to increased mortality risk after solid organ transplants, highlighting the need for further research. - **Individual Variability in Microbiome Responses**: The variability in gut microbiome responses to dietary interventions complicates the development of standardized treatments. - **Diversity in Research**: Underrepresentation of low- and middle-income countries in gut microbiome studies, limiting applicability of findings. - **Standardization of Measurements**: There are currently no standardized measures for assessing gut microbiome health, which poses challenges for clinical applications. - **Dysbiosis and Autoimmune Diseases**: Imbalances in gut microbiota can lead to altered immune responses, contributing to the development of autoimmune diseases. - **Circadian Rhythm Disruption**: Research indicates that lifestyle factors affecting circadian rhythms may increase colorectal cancer risk by altering gut microbiome composition. - **Antibiotic Impact on Microbiome**: Research indicates that antibiotics can disrupt gut microbiome health, affecting cognitive functions in aquatic species. - **Regulatory Concerns**: Challenges related to genomic data privacy and the need for rigorous validation of health claims associated with microbiome impacts. - **Consumer Understanding**: A survey revealed a significant gap in consumer knowledge regarding gut health and its connection to overall well-being. - **Environmental Pollutants**: Studies show that exposure to persistent organic pollutants can disrupt gut microbiome and lead to metabolic diseases. - **Regulatory Frameworks**: The need for harmonized regulatory frameworks for microbiome therapeutics to ensure safety and accessibility. - **Drug-Induced Dysbiosis**: Research indicates that certain drugs, like entacapone, can disrupt the gut microbiome, raising concerns about their long-term effects on gut health.