# Antibiotic Resistance * **Definition:** The ability of bacteria and other microorganisms to resist the effects of an antibiotic to which they were once sensitive, leading to treatment failures and increased risk of spread of infections. * **Taxonomy:** Healthcare Topics / Antibiotic Resistance ## News * Selected news on the topic of **Antibiotic Resistance**, for healthcare technology leaders * 2.9K news items are in the system for this topic * Posts have been filtered for tech and healthcare-related keywords | Date | Title | Source | | --- | --- | --- | | 5/20/2025 | [**Ambulatory Surgical & Emergency Center Services Market 2025: AI, Electrification, and ...**](https://www.linkedin.com/pulse/ambulatory-surgical-emergency-center-fotve/) | [[Linkedin]] | | 5/16/2025 | [**How Payer-Provider Collaboration is Creating A More Patient-Friendly Healthcare Industry**](https://hitconsultant.net/2025/05/16/how-payer-provider-collaboration-is-creating-a-more-patient-friendly-healthcare-industry/) | [[HIT Consultant]] | | 5/12/2025 | [**With CDC advisory panel disbanded, doctors fear impact: 'Long live hospital infections'**](https://www.chiefhealthcareexecutive.com/view/with-cdc-advisory-panel-disbanded-doctors-fear-impact-long-live-hospital-infections-) | [[Chief Healthcare Executive]] | | 4/30/2025 | [**National-level actions found to be effective at tackling antibiotic resistance**](https://medicalxpress.com/news/2025-04-national-actions-effective-tackling-antibiotic.html) | [[MedicalXpress]] | | 4/16/2025 | [**Innovative computational tool uses long-read sequencing to track antibiotic resistance genes**](https://phys.org/news/2025-04-tool-sequencing-track-antibiotic-resistance.html) | [[Phys Org]] | | 4/16/2025 | [**Innovative computational tool uses long-read sequencing to track antibiotic resistance genes**](https://phys.org/news/2025-04-tool-sequencing-track-antibiotic-resistance.html?deviceType=desktop) | [[Phys Org]] | | 3/19/2025 | [**Global Bacteriophage Market Set to Reach USD 72.4 Million by 2035, Driven by ... - Yahoo Finance**](https://finance.yahoo.com/news/global-bacteriophage-market-set-reach-123000342.html) | [[Yahoo Finance]] | | 2/10/2025 | [**Antibiotics Market to Grow by USD 18.22 Billion (2025-2029), Driven by Rising Infectious Diseases, with AI Redefining the Market Landscape - Technavio**](https://www.prnewswire.com/news-releases/antibiotics-market-to-grow-by-usd-18-22-billion-2025-2029-driven-by-rising-infectious-diseases-with-ai-redefining-the-market-landscape---technavio-302371972.html) | [[PR Newswire]] | | 2/10/2025 | [**Oysters could help combat antibiotic resistance - Yahoo**](https://www.yahoo.com/news/oysters-could-help-combat-antibiotic-070030425.html) | [[Yahoo]] | | 1/30/2025 | [**Osta Therapeutics Strengthens Leadership Team with Two Industry Experts Supporting its Goal of Addressing Antibiotic Resistance**](http://www.businesswire.com/news/home/20250130209803/en/Osta-Therapeutics-Strengthens-Leadership-Team-with-Two-Industry-Experts-Supporting-its-Goal-of-Addressing-Antibiotic-Resistance/?feedref=JjAwJuNHiystnCoBq_hl-RLXHJgazfQJNuOVHefdHP-D8R-QU5o2AvY8bhI9uvWSD8DYIYv4TIC1g1u0AKcacnnViVjtb72bOP4-4nHK5ieT3WxPE8m_kWI77F87CseT) | [[Business Wire]] | | 1/29/2025 | [**Genetic fingerprint could help predict antibiotic resistance in bacteria**](https://www.news-medical.net/news/20250129/Genetic-fingerprint-could-help-predict-antibiotic-resistance-in-bacteria.aspx) | [[News Medical Net]] | | 1/14/2025 | [**Anticoagulant Reversal Drugs Market to Grow by USD 1.27 Billion from 2025-2029, Driven by Rising Coagulation Disorders and AI-Redefined Market Landscape - Technavio**](https://www.prnewswire.com/news-releases/anticoagulant-reversal-drugs-market-to-grow-by-usd-1-27-billion-from-2025-2029--driven-by-rising-coagulation-disorders-and-ai-redefined-market-landscape---technavio-302349090.html) | [[PR Newswire]] | | 12/13/2024 | [**Soil ecosystems fuel antibiotic resistance development**](https://www.news-medical.net/news/20241213/Soil-ecosystems-fuel-antibiotic-resistance-development.aspx) | [[News Medical Net]] | | 12/12/2024 | [**How soil bacteria contribute to the growing global issue of antibiotic resistance**](https://phys.org/news/2024-12-soil-bacteria-contribute-global-issue.html) | [[Phys Org]] | | 12/12/2024 | [**The lab effect: How an efficient and effective lab strengthens your hospital's success**](https://www.beckershospitalreview.com/patient-safety-outcomes/the-lab-effect-how-an-efficient-and-effective-lab-strengthens-your-hospitals-success.html) | [[Beckers Hospital Review]] | | 11/25/2024 | [**Singapore General Hospital developing AI to prevent antibiotic resistance**](https://www.healthcareitnews.com/news/asia/singapore-general-hospital-developing-ai-prevent-antibiotic-resistance) | [[Healthcare IT News]] | | 11/24/2024 | [**Risk perception and antibiotic resistance: Bridging knowledge and action**](https://medicalxpress.com/news/2024-11-perception-antibiotic-resistance-bridging-knowledge.html) | [[MedicalXpress]] | | 11/18/2024 | [**Zymo Research Leads the Way in Wastewater Innovation as Key Sponsor of the Microbes in ...**](https://www.prnewswire.com/news-releases/zymo-research-leads-the-way-in-wastewater-innovation-as-key-sponsor-of-the-microbes-in-wastewater-symposium-2025-302307927.html) | [[PR Newswire]] | | 11/17/2024 | [**Zymo Research Leads the Way in Wastewater Innovation as Key Sponsor of the Microbes in Wastewater Symposium 2025**](https://finance.yahoo.com/news/zymo-research-leads-way-wastewater-130000124.html) | [[Yahoo Finance]] | | 11/15/2024 | [**Scientists propose drug-free method to combat antibiotic-resistant bacteria**](https://phys.org/news/2024-11-scientists-drug-free-method-combat.html) | [[Phys Org]] | | 11/6/2024 | [**Sewage surveillance for combating antimicrobial resistance proves more powerful than individual testing**](https://medicalxpress.com/news/2024-11-sewage-surveillance-combating-antimicrobial-resistance.html) | [[MedicalXpress]] | | 11/6/2024 | [**Sewage surveillance for combating antimicrobial resistance proves more powerful than ...**](https://medicalxpress.com/news/2024-11-sewage-surveillance-combating-antimicrobial-resistance.html?deviceType=desktop) | [[MedicalXpress]] | | 10/15/2024 | [**Innovation at a price: The hidden costs of antibiotic development**](https://medicalxpress.com/news/2024-10-price-hidden-antibiotic.html) | [[MedicalXpress]] | | 10/7/2024 | [**Single-cell genomics unveils secrets of the human microbiome**](https://www.news-medical.net/news/20241007/Single-cell-genomics-unveils-secrets-of-the-human-microbiome.aspx) | [[News Medical Net]] | | 6/14/2024 | [**Infection Surveillance Solutions Market to Reach $1,100 Million by 2027, Driven by Robust 13.8% CAGR**](http://prsync.com/marketsandmarkets---hc/infection-surveillance-solutions-market-to-reach--million-by--driven-by-robust--cagr-4174560/) | [[PRSync]] | ## Topic Overview (Some LLM-derived content — please confirm with above primary sources) ### Key Players - **Tulane University**: Research institution that discovered a genetic signature in bacteria predicting antibiotic resistance. - **Thermo Fisher Scientific**: A key player in the microbiology culture market, investing in innovative solutions to address antibiotic resistance. - **Merck**: Another major player in antibiotic development, focusing on both gram-positive and gram-negative bacteria. - **GlaxoSmithKline**: A leading pharmaceutical company involved in antibiotic development targeting resistant bacterial strains. - **Rice University**: Researchers developed an RNA barcoding method to track gene transfer in microbial communities, enhancing understanding of antibiotic resistance. - **BioInnovation Institute (BII)**: A collaborative organization providing funding and expertise for research projects aimed at combating antibiotic resistance. - **ArrePath, Inc.**: A biotechnology company focused on anti-infective discovery, aiming to combat antimicrobial resistance through advanced technologies. - **Zymo Research Corporation**: Company sponsoring the Microbes in Wastewater Symposium to address antibiotic resistance through wastewater surveillance. - **AUROBAC THERAPEUTICS**: A biopharmaceutical company focused on developing innovative treatments for bacterial infections and antimicrobial resistance. - **GARDP**: The Global Antibiotic Research & Development Partnership, which focuses on developing and making accessible antibiotic treatments. - **Visby Medical**: A company focused on developing rapid PCR diagnostics to combat antibiotic resistance, particularly in sexually transmitted infections. - **Baxter International Inc.**: A healthcare company launching new injectable pharmaceuticals aimed at addressing unmet patient needs, including those related to antibiotic resistance. - **Clarametyx Biosciences Inc.**: A company developing a non-antibiotic therapeutic and vaccine platform aimed at addressing persistent bacterial infections and combating antibiotic resistance. - **CARB-X**: A global non-profit partnership that supports early-stage antibacterial research and development, focusing on innovative therapeutics to combat drug-resistant bacteria. - **Informuta Inc.**: Startup founded by Kalen Hall, focused on developing a machine learning model to predict antibiotic resistance. - **Illumina**: A leader in sequencing technologies, contributing to advancements in metagenomics and antibiotic resistance research. - **Creative Diagnostics**: A leading supplier of Beta Lactamase Inhibitors, providing solutions for research and diagnostic applications. - **Debiopharm**: A biopharmaceutical company collaborating with GARDP to develop new antibiotics targeting multidrug-resistant Neisseria gonorrhoeae. - **T2 Biosystems, Inc.**: A company specializing in rapid diagnostics for sepsis-causing pathogens and antibiotic resistance detection using proprietary T2 Magnetic Resonance technology. - **Armata Pharmaceuticals, Inc.**: A biopharmaceutical company focused on developing bacteriophage therapeutics for antibiotic-resistant infections. ### Partnerships and Collaborations - **GENERARE Bioscience**: Collaborating with AUROBAC THERAPEUTICS to enhance research capabilities in antimicrobial resistance. - **AMR Accelerator**: A public-private partnership focused on coordinated action and funding to combat antimicrobial resistance. - **BII, MIT, and UNC**: Collaborating on the Pivot project to explore the role of mucus in combating antibiotic resistance, with significant funding and expertise provided by BII. - **ArrePath and AI/ML**: ArrePath aims to leverage its AI/ML platform to enhance drug discovery efforts against antimicrobial resistance. - **GARDP and Debiopharm**: A memorandum of understanding to develop Debio 1453, a new antibiotic targeting multidrug-resistant gonorrhea. - **CARB-X and Visby Medical**: Visby Medical received funding from CARB-X to enhance its rapid diagnostics for antibiotic resistance. - **Meiji Seika Pharma and MPM BioImpact**: An investment agreement to support new technologies and virology strategies to combat antibiotic resistance. - **TARGET Initiative**: Funded by the U.S. Department of Health and Human Services, this initiative uses generative AI to accelerate antibiotic discovery. - **KAUST and Saudi Ministry of Health**: A multi-institutional study analyzing multidrug-resistant Klebsiella pneumoniae in Saudi Arabia. - **Phare Bio**: Leading the TARGET project in collaboration with MIT and Harvard's Wyss Institute to identify new antibiotic candidates. - **binx health and Massachusetts General Hospital**: Collaboration that demonstrated the effectiveness of rapid testing in reducing inappropriate antibiotic treatments for STIs. - **Singapore General Hospital, DXC Technology, and Synapxe**: Collaboration to develop AI-driven solutions for personalized antibiotic regimens. - **Day Zero Diagnostics and UC Irvine**: Collaborating to enhance pathogen identification and susceptibility prediction using advanced genomic techniques. - **African Medical Devices Forum (AMDF)**: An initiative aimed at improving international collaborations and regulatory harmonization for diagnostic tools in combating AMR. - **T2 Biosystems and Cardinal Health**: An exclusive agreement for the distribution of rapid diagnostics for sepsis-causing pathogens in the U.S. - **Aladdin Bioinformatics Foundation**: Co-hosting the Microbes in Wastewater Symposium with Zymo Research to foster innovation in public health. - **Bruker and Ridom GmbH**: Strategic collaboration to enhance NGS bioinformatics applications in microbiology, focusing on genomic bacterial strain differentiation. - **University of Lausanne**: Partnered with i-Seq Biotechnology to develop broad-spectrum vaccines and therapeutics. ### Innovations, Trends, and Initiatives - **Machine Learning for Resistance Prediction**: Informuta Inc. is developing a model to predict antibiotic resistance, enhancing treatment precision. - **Phage Therapy**: An emerging treatment utilizing bacteriophages to target and destroy antibiotic-resistant bacteria, gaining traction due to rising resistance rates. - **Antimicrobial Peptide Mixtures**: Research shows that using a combination of antimicrobial peptides can significantly reduce the likelihood of developing antibiotic resistance. - **Random Antimicrobial Peptide Mixtures**: Research shows these mixtures can reduce resistance evolution compared to single peptides. - **Preventive Biologics**: Innovative biologics developed to combat antibiotic resistance by improving patient outcomes and offering economic benefits over traditional antibiotics. - **Bacteriophage Therapy**: An emerging alternative to antibiotics, with significant market growth projected as a solution to antibiotic resistance. - **Nanopore Sequencing Technology**: Used to observe ribosomal RNA modifications in bacteria, highlighting innovative research methods to understand antibiotic resistance mechanisms. - **Single-Cell Genome Approach**: A novel methodology developed to enhance understanding of microbial interactions and antibiotic resistance gene profiling. - **Generative AI in Antibiotic Discovery**: The TARGET initiative aims to streamline the identification process of new antibiotic candidates. - **Sevelamer Research**: A study suggesting that sevelamer can mitigate antibiotic resistance by binding off-target antibiotics in the gut. - **Sewage Surveillance**: A method being explored to monitor antimicrobial resistance in waterborne diseases, providing insights into public health. - **High-Throughput Screening**: Utilized in antibiotic discovery to identify effective beta-lactam antibiotics and inhibitors. - **Keynome Platform**: Day Zero Diagnostics' platform predicts antimicrobial resistance from bacterial genomes, enhancing diagnostic capabilities. - **Bacteriophage Therapeutics**: Armata Pharmaceuticals is advancing bacteriophage therapies targeting specific antibiotic-resistant bacteria, with ongoing clinical trials. - **Rapid PCR Diagnostics**: Visby Medical's development of rapid PCR tests to identify antibiotic resistance mutations in infections. - **AI2D**: An AI-driven solution developed to provide personalized antibiotic recommendations, aiming to reduce unnecessary antibiotic prescriptions. - **Argo**: A computational tool developed by the University of Hong Kong to track antibiotic resistance genes in environmental samples, enhancing risk assessment. - **ABBIE Technology Kits**: SOHM, Inc. is developing kits for faster genetic integration, aiming to reduce costs and environmental impact in antibiotic resistance research. - **AI-based Group Association Model (GAM)**: Developed by Tulane University to enhance the identification of antibiotic resistance markers, improving treatment effectiveness. - **AI in Diagnostics**: University of Zurich's AI system, 'EUCAST-GPT-expert', aims to improve the detection of antibiotic-resistant bacteria. ### Challenges and Concerns - **Rising Antibiotic Resistance**: Antimicrobial resistance poses a significant global public health threat, necessitating urgent investments in new antibiotic development. - **Antibiotic Resistance Crisis**: Antibiotic resistance is projected to become a leading cause of global mortality, surpassing cancer deaths by 2050, necessitating urgent action. - **Antibiotic Misuse**: Continued misuse of antibiotics contributes to resistance, necessitating ongoing investment in antimicrobial stewardship programs. - **Antibiotic Shortages**: Shortages are disrupting patient care and increasing treatment costs, exacerbating the resistance crisis. - **Veterinary Antibiotic Resistance**: Growing concerns about antibiotic resistance in veterinary medicine, paralleling issues in human health. - **Misuse of Antibiotics**: Education gaps among healthcare professionals contribute to the misuse of antibiotics, worsening resistance. - **Microplastics and Antibiotic Resistance**: Research indicates that microplastics contribute to antibiotic resistance in bacteria, particularly in impoverished areas with limited sanitation. - **Global Health Crisis**: Antibiotic resistance is projected to become the leading cause of death by 2050, necessitating urgent action. - **Limited Antibiotic Pipeline**: High costs and lengthy R&D processes hinder the development of new antibiotics, exacerbating resistance issues. - **Antibiotic Overuse in Aged Care**: Research highlights the correlation between extensive antibiotic use in aged care facilities and the emergence of antibiotic-resistant bacteria. - **Heteroresistance**: A phenomenon complicating the detection and treatment of antibiotic resistance, where bacterial populations contain both susceptible and resistant cells. - **Global Health Threat**: The World Health Organization identifies antibiotic resistance as a major global health threat, complicating the treatment of infections. - **Multidrug-Resistant Organisms (MDROs)**: The rise of MDROs poses significant public health risks, with an estimated 4.71 million deaths linked to bacterial antimicrobial resistance in 2021. - **Environmental Impact**: The role of soil as a reservoir for antibiotic resistance genes, posing a public health threat through gene transfer to humans. - **Environmental Concerns**: Research indicates that environmental factors, such as beach sand containing antibiotic-resistant DNA, contribute to the spread of resistance. - **Rising Rates of Multi-Resistant Strains**: Meta-analyses reveal alarming rates of multi-resistant bacterial strains among children in Sub-Saharan Africa, highlighting the urgent need for improved epidemiological data. - **Regulatory Constraints**: Challenges in regulatory frameworks and data privacy hinder the adoption of innovative solutions in combating antibiotic resistance. - **Shortage of Blood Culture Bottles**: Hospitals face critical shortages of blood culture bottles essential for diagnosing bloodstream infections, potentially increasing antibiotic resistance. - **Overprescription of Antibiotics**: At least 28% of antibiotic prescriptions in the U.S. are unnecessary, highlighting the need for improved diagnostic tools and stewardship programs. ## Related Topics [[Antimicrobial Resistance]]